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Be sure to mention any of the following antihistamines; cimetidine tagamet ; diet pills; disulfiram antabuse ; guanethidine ismelin ; ipratropium atrovent ; quinidine quinidex ; medications for irregular heartbeats such as flecainide tambocor and propafenone rythmol ; medications for anxiety, asthma, colds, irritable bowel disease, mental illness, nausea, parkinson s disease, seizures, ulcers, or urinary problems; other antidepressants; phenobarbital bellatal, solfoton ; sedatives; selective serotonin reuptake inhibitors ssris such as citalopram celexa , fluoxetine prozac, sarafem , fluvoxamine luvox , paroxetine paxil , and sertraline zoloft ; sleeping pills; thyroid medications; and tranquilizers.

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Although changes in sexual desiresexual performance and sexual satisfaction often occur as manifestations of a psychiatric disorderthey may also be a consequence of SSRI treatmentHoweverreliable estimates of the incidence and severity of untoward experiences involving sexual desireperformance and satisfaction are difficult to obtainin part because patients and healthcare providers may be reluctant to discuss themAccordinglyestimates of the incidence of untoward sexual experience and performance cited in labeling may underestimate their actual incidence.

Studies at clinically relevant doses have demonstrated that sertraline blocks the uptake of serotonin into human plateletsIn vitro studies in animals also suggest that sertraline is a potent and selective inhibitor of neuronal serotonin reuptake and has only very weak effects on norepinephrine and dopamine neuronal reuptakeIn vitro studies have shown that sertraline has no significant affinity for adrenergicalpha1alpha2betacholinergicGABAdopaminergichistaminergicserotonergic5HT1A5HT1B5HT2or benzodiazepine receptorsThe chronic administration of sertraline was found in animals to down regulate brain norepinephrine receptorsSertraline does not inhibit monoamine oxidase.

Overallavailable published epidemiologic studies of pregnant women exposed to sertraline in the first trimester suggest no difference in major birth defect risk compared to the background rate for major birth defects in comparator populationsSome studies have reported increases for specific major birth defectshoweverthese study results are inconclusiveSee DataThere are clinical considerations regarding neonates exposed to SSRIs and SNRIsincluding ZOLOFTduring the third trimester of pregnancySee Clinical Considerations

Inform patients not to take disulfiram when taking ZOLOFT oral solutionConcomitant use is contraindicated due the alcohol content of the oral solutionsee CONTRAINDICATIONS

This medication can cause you to have a false positive drug screening testIf you provide a urine sample for drug screeningtell the laboratory staff that you are taking sertraline.

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examples of the ssri s include prozac fluoxetine , luvox fluvoxamine , paxil paroxetine , celexa citalopram , and zoloft sertraline .

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